Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | SNCA | P37840 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RYR2 | Q92736 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089116 | 0.72 | KDM1A (0.38) | KDM4EHTTMAOAMAOBSNCA | |
| SCHEMBL31289101 | 0.71 | KDM4E (0.41) | KDM4EHTTMAOAMAOBSNCA | |
| SCHEMBL4133299 | 0.69 | GAA (0.50) | MAOAMAOBGAACA2CA12 | |
| SCHEMBL31463289 | 0.69 | GAA (0.50) | MAOAMAOBGAACA2CA12 | |
| SCHEMBL9782047 | 0.69 | KDM4E (0.45) | KDM4EHTTMAOAMAOBSNCA | |
| SCHEMBL6269222 | 0.69 | SNCA (0.41) | KDM4EHTTMAOAMAOBSNCA | |
| SCHEMBL1479378 | 0.67 | MAOA (0.50) | MAOAMAOBGAA | |
| SCHEMBL8884488 | 0.66 | CA2 (0.50) | KDM4EMAOAMAOBGAAALDH1A1 | |
| SCHEMBL28445528 | 0.66 | STS (0.60) | KDM4ELMNAGAAALDH1A1MEN1 | |
| SCHEMBL1448079 | 0.66 | CYP11B1 (0.39) | KDM4EMAOAMAOBLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110372722-A | A method of synthesis sulfur-bearing nitrogen bis-heterocyclic compound | 河南师范大学 | 2019-10-25 | — | — | CN | disclosed |