Sugi Predict

Sugi Predict / Compounds / SCHEMBL288785

SCHEMBL288785

SCHEMBL288785

CCOC(=O)c1sc(Br)nc1C

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.59
▸ HPGD P15428 3/20 0.59
▸ KDM4E B2RXH2 4/20 0.57
▸ MAPT P10636 3/20 0.57
▸ NPSR1 Q6W5P4 2/20 0.57
▸ DHODH Q02127 1/20 0.57
▸ HSD17B10 Q99714 1/20 0.56
▸ CDC7 O00311 1/20 0.55
▸ DBF4 Q9UBU7 1/20 0.55
▸ NPC1 O15118 2/20 0.54
▸ RAB9A P51151 1/20 0.52
▸ MEN1 O00255 2/20 0.52
▸ KMT2A Q03164 2/20 0.52
▸ CYP1A2 P05177 1/20 0.51
▸ LMNA P02545 3/20 0.51
▸ TSHR P16473 1/20 0.51
▸ SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25290183 0.88 TSHR (0.48) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL622325 0.85 ALDH1A1 (0.51) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL1919483 0.84 ALDH1A1 (0.68) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL12034449 0.83 CDC7 (0.69) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL2498385 0.83 NPC1 (0.72) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL23708646 0.82 ALDH1A1 (0.49) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL27848208 0.82 ALDH1A1 (0.60) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL23214292 0.82 LMNA (0.49) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL1921091 0.82 ALDH1A1 (0.49) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL27899564 0.81 ALDH1A1 (0.59) ALDH1A1HPGDKDM4EMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116874-A1 HETEROAROMATIC INDOLESULFONAMIDES SEED THERAPEUTICS INC (US) 2026-04-30 — — US disclosed
US-12583887-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-03-24 — — US disclosed
EP-4704836-A1 HETEROAROMATIC INDOLESULFONAMIDES Seed Therapeutics, Inc (US) 2026-03-11 — — EP disclosed
US-12565494-B2 Inhibitors of human respiratory syncytial virus and metapneumovirus MERCK SHARP & DOHME LLC 2026-03-03 — — US disclosed
US-12559521-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-02-24 — — US disclosed
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 — — US disclosed
US-20250320224-A1 NOVEL PAR-2 INHIBITORS DOMAIN THERAPEUTICS (FR) 2025-10-16 — — US disclosed
US-20250289789-A1 REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. 2025-09-18 — — US disclosed
CN-120192331-A E3 ubiquitin ligase CRBN ligand and application thereof 苏州美诺医药科技有限公司 2025-06-24 — — CN disclosed
CN-119954793-A Compounds as xanthine oxidase inhibitors and uses thereof 广州市联瑞制药有限公司 2025-05-09 — — CN disclosed
WO-2002024200-A1 SUBSTITUTED AZOLE DERIVATIVES AS INHIBITORS OF CORTICOTROPIN RELEASING FACTOR BRISTOL-MYERS SQUIBB COMPANY (US) 2002-03-28 — — WO disclosed
EP-1169038-A1 CYCLIC PROTEIN TYROSINE KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2002-01-09 — — EP disclosed
EP-1135377-A1 NOVEL COMPOUNDS AstraZeneca AB (SE) 2001-09-26 — — EP disclosed
EP-1124827-A1 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS Dow AgroSciences LLC (US) 2001-08-22 — — EP disclosed
WO-2000062778-A1 CYCLIC PROTEIN TYROSINE KINASE INHIBITORS BRISTOL-MYERS SQUIBB CO. (US) 2000-10-26 — — WO disclosed
US-6096898-A One pot synthesis of 1,2,4-triazoles DOW AGROSCIENCES LLC (US) 2000-08-01 — — US disclosed
WO-2000034254-A1 NOVEL COMPOUNDS ASTRAZENECA AB (SE) 2000-06-15 — — WO disclosed
WO-2000024739-A1 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS DOW AGROSCIENCES LLC (US) 2000-05-04 — — WO disclosed
US-4077968-A ANTIINFLAMMATORY, ANTIRHEUMATIC, ANALGESIC, ANTILIPEMIC SHIONOGI & CO., LTD. (JA) 1978-03-07 — — US disclosed
US-4025528-A ANTIINFLAMMATORY, ANALGESIC, ANTILIPEMIC SHIONOGI & CO., LTD. (JA) 1977-05-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289789-A1 REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF CDK2, CDK20, CDK1 ALDH1A1 3042/4885HPGD 1315/4885KDM4E 173/4885
US-20250320224-A1 NOVEL PAR-2 INHIBITORS F2RL1, F2R, F2RL3 ALDH1A1 1534/4885HPGD 249/4885KDM4E 4042/4885
US-12559521-B2 PSMA imaging agents KLK3, PSMA1, PSMA6 ALDH1A1 2393/4885HPGD 1527/4885KDM4E 2567/4885
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP9, DPP7, DPP4 ALDH1A1 245/4885HPGD 2941/4885KDM4E 3047/4885
US-12583887-B2 PSMA imaging agents KLK3, PSMA3, PSMA1 ALDH1A1 2109/4885HPGD 1518/4885KDM4E 1551/4885
US-20260116874-A1 HETEROAROMATIC INDOLESULFONAMIDES DCAF1, DCAF15, DDX39B ALDH1A1 1025/4885HPGD 4868/4885KDM4E 575/4885
US-12565494-B2 Inhibitors of human respiratory syncytial virus and metapneumovirus NHERF1, ZC3HAV1, SARS1 ALDH1A1 4313/4885HPGD 2414/4885KDM4E 3725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.