Formic Acid

Formic Acid

SCHEMBL28878596

NCc1ccc(-c2cccc(CO)c2)c(CN)c1.O=CO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.41
PRKCI P41743 1/20 0.39
ACMSD Q8TDX5 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA7 P36544 1/20 0.37
DPP4 P27487 1/20 0.37
ENPP2 Q13822 1/20 0.37
CFD P00746 6/20 0.36
F11 P03951 2/20 0.36
TPSB2 P20231 2/20 0.36
PLG P00747 1/20 0.36
PLAU P00749 1/20 0.36
KLKB1 P03952 1/20 0.36
F7 P08709 1/20 0.36
PI4K2A Q9BTU6 1/20 0.36
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35
FYN P06241 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28329381 0.93 CSNK2A1 (0.46) CSNK2A1PRKCIACMSDCHRNB4CHRNA3
Formic Acid SCHEMBL28329379 0.86 DPP4 (0.54) PRKCIACMSDDPP4CFDF11
Formic Acid SCHEMBL28330628 0.83 MTNR1B (0.43) FYNTAAR1
Formic Acid SCHEMBL28878581 0.83 PTGDR2 (0.40) TAAR1
SCHEMBL20530624 0.78 MAP2K4 (0.47) PRKCIACMSDCHRNB4CHRNA3CHRNA7
SCHEMBL20530656 0.78 PNMT (0.43) CSNK2A1PRKCIDPP4FYNTAAR1
Formic Acid SCHEMBL28329378 0.76 LTB4R (0.41) PRKCITAAR1
SCHEMBL30466818 0.75 MGAT2 (0.47) FYNTAAR1
SCHEMBL20530647 0.75 S1PR1 (0.43) PRKCITAAR1
SCHEMBL30466804 0.75 S1PR1 (0.43) PRKCITAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110494442-A The big ring of peptide and its purposes in treatment bacterium infection HOFFMANN LA ROCHE 2019-11-22 CN disclosed