SCHEMBL28878600

SCHEMBL28878600

CC1=Cc2c(-c3cc(C)cc(C)c3)cccc2C1[SiH](C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28878599 1.00 BRD4 (0.32) BRD4CREBBP
SCHEMBL29258739 0.85 HTR1A (0.33)
SCHEMBL27494089 0.84 PDCD1 (0.34) BRD4
SCHEMBL28918323 0.84
SCHEMBL8468224 0.83 PDCD1 (0.33) BRD4
SCHEMBL28050155 0.83 RXRB (0.32)
SCHEMBL29032467 0.82 HTR1A (0.38)
Hydrochloric Acid SCHEMBL5169310 0.82 PDCD1 (0.33) BRD4
SCHEMBL5862311 0.80 BRD9 (0.34) BRD4CREBBP
SCHEMBL27459241 0.79 PDCD1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110177798-B Catalyst and process for preparing same 博里利斯股份公司 2022-08-30 CN disclosed