Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 5/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HTR2B | P41595 | 4/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19837031 | 1.00 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRNB4CHRNA3HTR2C | |
| SCHEMBL28879111 | 1.00 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRNB4CHRNA3HTR2C | |
| SCHEMBL29962079 | 1.00 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRNB4CHRNA3HTR2C | |
| SCHEMBL7966941 | 0.79 | HTR2C (0.51) | HTR2CNCF1 | |
| SCHEMBL19837189 | 0.71 | TLR7 (0.55) | CHRNB2CHRNA4CHRNB4CHRNA3HTR2C | |
| SCHEMBL14921560 | 0.67 | METAP2 (0.47) | CHRNB2CHRNA4NCF1 | |
| SCHEMBL17300871 | 0.66 | CHRNB4 (0.52) | CHRNB2CHRNA4CHRNB4CHRNA3HTR2C | |
| SCHEMBL30019238 | 0.64 | METAP2 (0.55) | — | |
| SCHEMBL3462719 | 0.64 | AURKA (0.41) | HTR2AHTR2B | |
| SCHEMBL31382556 | 0.63 | NCF1 (0.53) | NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563075-B | TLR7/8 antagonists and uses thereof | 默克专利股份公司 | 2022-09-30 | — | — | CN | disclosed |