Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | OGA | O60502 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29805447 | 0.83 | CNR1 (0.46) | CNR1CNR2HSD11B1CDK5CDK5R1 | |
| SCHEMBL14879935 | 0.83 | CNR1 (0.49) | CNR1CNR2HSD11B1CDK5CDK5R1 | |
| SCHEMBL25285477 | 0.83 | KIF18A (0.52) | CDK5CDK5R1KIF18AMEN1KMT2A | |
| SCHEMBL23451255 | 0.83 | ADORA2A (0.55) | CNR1CNR2HSD11B1CDK5CDK5R1 | |
| SCHEMBL18654355 | 0.82 | CNR1 (0.46) | CNR1CNR2HSD11B1CDK5CDK5R1 | |
| SCHEMBL12075887 | 0.77 | KIF18A (0.51) | CNR1CNR2KIF18A | |
| SCHEMBL28535502 | 0.76 | MEN1 (0.63) | RAB9AMEN1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL22146027 | 0.76 | NUDT1 (0.47) | CNR1CNR2HSD11B1SYK | |
| SCHEMBL12075897 | 0.76 | TYK2 (0.44) | KIF18AOGA | |
| SCHEMBL23599390 | 0.76 | NPC1 (0.49) | CNR1CNR2RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279756-A | METTL3 modulators | 埃克森特治疗公司 | 2022-11-01 | — | — | CN | disclosed |