Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28879364 | 0.98 | CARM1 (0.35) | HRH3L3MBTL1CARM1PRMT6PRMT8 | |
| SCHEMBL8553534 | 0.87 | HRH3 (0.44) | HRH3L3MBTL1CARM1PRMT6PRMT8 | |
| SCHEMBL10658133 | 0.85 | CARM1 (0.41) | HRH3L3MBTL1CARM1PRMT6PRMT8 | |
| SCHEMBL23278171 | 0.82 | HRH3 (0.39) | HRH3L3MBTL1CARM1PRMT6PRMT8 | |
| SCHEMBL28958203 | 0.81 | KEAP1 (0.42) | MEN1KMT2AALDH1A1MAPTANPEP | |
| SCHEMBL28879365 | 0.81 | SMN1; SMN2 (0.37) | MEN1KMT2AALDH1A1ANPEPERAP2 | |
| SCHEMBL20354500 | 0.79 | CARM1 (0.37) | HRH3L3MBTL1CARM1PRMT6PRMT8 | |
| SCHEMBL11036023 | 0.78 | HRH3 (0.56) | HRH3L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL10207845 | 0.77 | HRH3 (0.40) | HRH3THRB | |
| SCHEMBL4119651 | 0.77 | ALOX15 (0.40) | HRH3L3MBTL1CARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286571-A | Chloroquine derivative and preparation method thereof | 华南理工大学 | 2022-11-04 | — | — | CN | claimed |
| CN-115286571-A | Chloroquine derivative and preparation method thereof | 华南理工大学 | 2022-11-04 | — | — | CN | disclosed |