Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4332123 | 0.88 | SMN1; SMN2 (0.48) | KEAP1SMN1; SMN2ALDH1A1KDM4EANPEP | |
| SCHEMBL13668438 | 0.83 | KDM4E (0.53) | KEAP1SMN1; SMN2ALDH1A1KDM4EANPEP | |
| SCHEMBL28879364 | 0.82 | CARM1 (0.35) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28879372 | 0.81 | HRH3 (0.38) | ALDH1A1ANPEPMEN1KMT2AMAPT | |
| SCHEMBL10505610 | 0.81 | KEAP1 (0.55) | KEAP1SMN1; SMN2ALDH1A1KDM4EANPEP | |
| SCHEMBL23278175 | 0.81 | KEAP1 (0.45) | KEAP1SMN1; SMN2ALDH1A1KDM4EANPEP | |
| SCHEMBL23396624 | 0.81 | KEAP1 (0.55) | KEAP1SMN1; SMN2ALDH1A1KDM4EUSP2 | |
| SCHEMBL20283834 | 0.80 | KEAP1 (0.46) | KEAP1SMN1; SMN2ALDH1A1KDM4ETSHR | |
| SCHEMBL32670462 | 0.80 | ALDH1A1 (0.39) | KEAP1SMN1; SMN2ALDH1A1KDM4ETSHR | |
| SCHEMBL17819447 | 0.79 | USP2 (0.48) | KEAP1SMN1; SMN2ALDH1A1KDM4EANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286571-A | Chloroquine derivative and preparation method thereof | 华南理工大学 | 2022-11-04 | — | — | CN | claimed |
| CN-115286571-A | Chloroquine derivative and preparation method thereof | 华南理工大学 | 2022-11-04 | — | — | CN | disclosed |