Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17489961 | 0.90 | HSPA1A (0.40) | P2RX4SMN1; SMN2KDM4EMAPTMEN1 | |
| SCHEMBL8108033 | 0.86 | P2RX4 (0.53) | P2RX4SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL28335973 | 0.83 | P2RX4 (0.46) | P2RX4SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL8584047 | 0.81 | P2RX4 (0.49) | P2RX4SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL24255049 | 0.77 | ALDH1A1 (0.48) | P2RX4SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL15434761 | 0.77 | MGLL (0.40) | P2RX4SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL18389066 | 0.77 | MAPT (0.46) | P2RX4SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL20308236 | 0.77 | HSPA1A (0.31) | P2RX4HSPA1APABPC1 | |
| SCHEMBL6123819 | 0.76 | P2RX4 (0.47) | P2RX4SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL21765588 | 0.75 | GAA (0.45) | P2RX4SMN1; SMN2KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437172-A | A kind of 3,7- bis- replaces phenoxazine analog derivative and preparation method thereof | UNIV ZHENGZHOU | 2019-11-12 | — | — | CN | disclosed |