Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.53 |
| ▸ | GGT1 | P19440 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885742 | 0.89 | PTGS2 (0.60) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL10492960 | 0.89 | PTGS2 (0.60) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL15267403 | 0.85 | PTGS2 (0.63) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| Phenylaspirinate SCHEMBL29389369 | 0.84 | HSD17B10 (0.75) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| Phenylaspirinate SCHEMBL25954 | 0.84 | HSD17B10 (0.75) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL21449134 | 0.83 | PTGS2 (0.68) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL11521148 | 0.83 | KDM4E (0.73) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL4134586 | 0.79 | PTGS2 (0.80) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL4125810 | 0.79 | HSD17B10 (0.66) | PTGS2HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL811872 | 0.79 | KDM4E (0.69) | PTGS2HSD17B10KDM4ELMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022115952-A1 | [1-(4-CHLORO-BENZOYL)-5-METHOXY-2-METHYL-1H-INDOL-3-YL]-ACETIC ACID 4-THIOCARBAMOYL-PHENYL ESTER FOR THE TREATMENT OF A VIRAL INFECTION | ANTIBE THERAPEUTICS INC. (CA) | 2022-06-09 | — | — | WO | disclosed |
| US-8541398-B2 | Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs | ANTIBE THERAPEUTICS INC. (CA) | 2013-09-24 | — | — | US | disclosed |
| US-8541398-B2 | Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs | ANTIBE THERAPEUTICS INC. (CA) | 2013-09-24 | — | — | US | disclosed |
| US-8541398-B2 | Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs | ANTIBE THERAPEUTICS INC. (CA) | 2013-09-24 | — | — | US | disclosed |
| EP-2057139-B1 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | ANTIBE THERAPEUTICS INC (US) | 2013-09-04 | — | — | EP | disclosed |
| EP-2057139-B1 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | ANTIBE THERAPEUTICS INC (US) | 2013-09-04 | — | — | EP | disclosed |
| US-8314140-B2 | 4-hydroxythiobenzamide derivatives of drugs | ANTIBE THERAPEUTICS INC. (CA) | 2012-11-20 | — | — | US | disclosed |
| US-8314140-B2 | 4-hydroxythiobenzamide derivatives of drugs | ANTIBE THERAPEUTICS INC. (CA) | 2012-11-20 | — | — | US | disclosed |
| US-8314140-B2 | 4-hydroxythiobenzamide derivatives of drugs | ANTIBE THERAPEUTICS INC. (CA) | 2012-11-20 | — | — | US | disclosed |
| CN-101490029-B | 4-hydroxythiobenzamide derivatives of drugs | ANTIBE THERAPEUTICS INC | 2012-07-04 | — | — | CN | disclosed |
| CN-101490029-A | 4-hydroxythiobenzamide derivatives of drugs | ANTIBE THERAPEUTICS INC (CA) | 2009-07-22 | — | — | CN | disclosed |
| EP-2057139-A1 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | Antibe Therapeutics Inc. (US) | 2009-05-13 | — | — | EP | disclosed |
| EP-2041108-A1 | 4-HYDROXYTHIOBENZAMIDE DERIVATIVES OF DRUGS | Antibe Therapeutics Inc. (US) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008009118-A1 | 4-HYDROXYTHIOBENZAMIDE DERIVATIVES OF DRUGS | ANTIBE THERAPEUTICS INC. (CA) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008009118-A1 | 4-HYDROXYTHIOBENZAMIDE DERIVATIVES OF DRUGS | ANTIBE THERAPEUTICS INC. (CA) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008009127-A1 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | ANTIBE THERAPEUTICS INC. (CA) | 2008-01-24 | — | — | WO | disclosed |
| WO-2008009127-A1 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | ANTIBE THERAPEUTICS INC. (CA) | 2008-01-24 | — | — | WO | disclosed |
| US-20080004245-A1 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | ANTIBE THERAPEUTICS INC. (CA) | 2008-01-03 | — | — | US | disclosed |
| US-20080004245-A1 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | ANTIBE THERAPEUTICS INC. (CA) | 2008-01-03 | — | — | US | disclosed |
| US-20080004245-A1 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | ANTIBE THERAPEUTICS INC. (CA) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004245-A1 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | PTGS1, HPGDS, PTGES | PTGS2 4/4885HSD17B10 187/4885KDM4E 3781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.