SCHEMBL28880000

SCHEMBL28880000

O=Cc1ccc(O)c(-c2ccccc2)c1C=O

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.45
TRIM33 Q9UPN9 1/20 0.45
ERN1 O75460 14/20 0.42
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.38
BLM P54132 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
HSP90AA1 P07900 1/20 0.38
IDO1 P14902 1/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PADI4 Q9UM07 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16096807 0.83 ERN1 (0.48) TRIM24TRIM33ERN1MEN1KMT2A
SCHEMBL547871 0.79 LMNA (0.39) TRIM24TRIM33ERN1MEN1KMT2A
SCHEMBL27902277 0.79 HDAC4 (0.47) TRIM24TRIM33ERN1MEN1KMT2A
SCHEMBL6267216 0.77 TRIM24 (0.59) TRIM24TRIM33ERN1MEN1KMT2A
SCHEMBL27202109 0.76 TRIM24 (0.40) TRIM24TRIM33ERN1MEN1KMT2A
SCHEMBL547876 0.74 PTGS2 (0.39) ERN1MEN1KMT2ALMNATHRB
SCHEMBL3451683 0.73 ERN1 (0.50) TRIM24TRIM33ERN1MEN1KMT2A
Fomecin B SCHEMBL11039474 0.73 ERN1 (0.54) TRIM24TRIM33ERN1MEN1KMT2A
SCHEMBL12679971 0.73 LMNA (0.50) ERN1MEN1KMT2ALMNATHRB
SCHEMBL1760592 0.72 ESR2 (0.53) MEN1KMT2ALMNABLMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115128750-A Anti-static optical cable and preparation method thereof 刘敏敏 2022-09-30 CN claimed
CN-115128750-A Anti-static optical cable and preparation method thereof 刘敏敏 2022-09-30 CN disclosed
CN-115128750-A Anti-static optical cable and preparation method thereof 刘敏敏 2022-09-30 CN disclosed