Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.33 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880207 | 0.82 | GABRP (0.38) | SLC1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11803807 | 0.76 | HDAC1 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11838982 | 0.74 | TSHR (0.33) | SLC1A2TSHR | |
| SCHEMBL9558856 | 0.74 | MMP12 (0.49) | SLC1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3453636 | 0.74 | FOLH1 (0.43) | SLC1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11805570 | 0.73 | AKR1B1 (0.46) | TSHRALDH1A1 | |
| SCHEMBL653330 | 0.72 | GABRP (0.41) | SLC1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29041505 | 0.71 | FOLH1 (0.43) | SLC1A2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29530823 | 0.71 | SLC1A2 (0.58) | SLC1A2FOLH1GRM3 | |
| SCHEMBL29199879 | 0.70 | ALOX15 (0.39) | SLC1A2GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549077-B | Production process of 4-chloropyrrolo [2,3-d ] pyrimidine | 浙江倍合德制药有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-113549077-B | Production process of 4-chloropyrrolo [2,3-d ] pyrimidine | 浙江倍合德制药有限公司 | 2022-11-11 | — | — | CN | disclosed |