Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.30 |
| ▸ | CLK1 | P49759 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23526088 | 0.81 | MLYCD (0.43) | MLYCDRORCGPBAR1CLK1DYRK1A | |
| SCHEMBL29945782 | 0.81 | MLYCD (0.43) | MLYCDRORCGPBAR1CLK1DYRK1A | |
| SCHEMBL28880379 | 0.81 | KIF11 (0.40) | THRATHRBNOTUM | |
| SCHEMBL31643114 | 0.74 | MLYCD (0.40) | MLYCDEPHX2NOTUM | |
| SCHEMBL28668894 | 0.74 | MLYCD (0.40) | MLYCDEPHX2NOTUM | |
| SCHEMBL31073566 | 0.72 | MLYCD (0.56) | MLYCDRORCGPBAR1EPHX2NOTUM | |
| SCHEMBL30014266 | 0.72 | MLYCD (0.38) | MLYCDEPHX2 | |
| SCHEMBL25839091 | 0.72 | MLYCD (0.38) | MLYCDEPHX2 | |
| SCHEMBL5367773 | 0.71 | MLYCD (0.51) | MLYCDGPBAR1CLK1DYRK1ADYRK1B | |
| SCHEMBL28880369 | 0.70 | SLC9A1 (0.31) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |