Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | EGFR | P00533 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4357581 | 0.77 | ALDH1A1 (0.69) | HTTALDH1A1LMNASMN1; SMN2PIK3CD | |
| SCHEMBL28340619 | 0.71 | FYN (0.69) | HTTALDH1A1EGFRLMNANCOA1 | |
| SCHEMBL14300929 | 0.70 | HTT (1.00) | HTTALDH1A1LMNASMN1; SMN2PIK3CD | |
| SCHEMBL4354965 | 0.70 | EGFR (0.70) | HTTALDH1A1EGFRLMNASMN1; SMN2 | |
| SCHEMBL20540478 | 0.68 | HTT (0.53) | HTTALDH1A1EGFRLMNASMN1; SMN2 | |
| SCHEMBL2990411 | 0.68 | EGFR (1.00) | EGFRFYNSRCERBB2BLK | |
| SCHEMBL16167178 | 0.68 | SIGMAR1 (0.41) | ALDH1A1EGFRLMNABTKKDR | |
| SCHEMBL13283192 | 0.68 | HTT (0.78) | HTTALDH1A1EGFRLMNASMN1; SMN2 | |
| SCHEMBL29240828 | 0.68 | PIM1 (0.50) | EGFRLMNASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL3001528 | 0.68 | FYN (0.60) | EGFRFYNSRCERBB2BLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627731-A | 4-aminoquinazoline-linked acrylamide compound and preparation method and application thereof | 贵州大学 | 2019-12-31 | — | — | CN | disclosed |