Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.50 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | PRKACA | P17612 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | CDK8 | P49336 | 2/20 | 0.46 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | FYN | P06241 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29822663 | 0.74 | KDM4E (0.46) | NUDT1MAP2K1DYRK1BNTRK1RPS6KA3 | |
| SCHEMBL19048703 | 0.71 | USP7 (0.76) | MAP2K1DYRK1BNTRK1RPS6KA3MAP4K4 | |
| SCHEMBL14999132 | 0.68 | RAB9A (0.45) | MAP2K1DYRK1BNTRK1MAP4K4PRKACA | |
| SCHEMBL2144054 | 0.67 | NUDT1 (1.00) | NUDT1MAP2K1DYRK1BMAP4K4PRKACA | |
| SCHEMBL29822768 | 0.65 | KDR (0.40) | NUDT1MAP2K1DYRK1BNTRK1RPS6KA3 | |
| SCHEMBL29822761 | 0.65 | NUDT1 (0.39) | NUDT1MAP2K1DYRK1BNTRK1RPS6KA3 | |
| SCHEMBL29822889 | 0.65 | GAA (0.53) | NUDT1MAP2K1DYRK1BNTRK1RPS6KA3 | |
| SCHEMBL10584393 | 0.64 | NOS2 (0.48) | NUDT1CLK4USP7ADORA2AADORA1 | |
| SCHEMBL11377976 | 0.64 | SMN1; SMN2 (0.47) | NUDT1MAP2K1DYRK1BNTRK1RPS6KA3 | |
| SCHEMBL1318629 | 0.63 | AKT1 (0.53) | NTRK1RPS6KA3KDRFLT3LTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286629-B | Method for preparing medicine intermediate 3-anilioimidazole [1,2-a ] pyridine derivative through catalysis | 安徽工业大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-115286629-A | Method for preparing medical intermediate 3-phenylamino imidazole [1,2-a ] pyridine derivative through catalysis | 安徽工业大学 | 2022-11-04 | — | — | CN | disclosed |