Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5572601 | 0.83 | USP2 (0.47) | USP2SMN1; SMN2HPGDRECQLSTS | |
| SCHEMBL18294 | 0.81 | USP2 (0.69) | USP2SMN1; SMN2HPGDRECQLGPR119 | |
| SCHEMBL698803 | 0.81 | USP2 (0.69) | USP2SMN1; SMN2HPGDRECQLGPR119 | |
| SCHEMBL1024310 | 0.79 | USP2 (0.53) | USP2SMN1; SMN2HPGDRECQLGPR119 | |
| SCHEMBL56379 | 0.79 | USP2 (0.53) | USP2SMN1; SMN2HPGDSTSGPR119 | |
| SCHEMBL11339897 | 0.78 | USP2 (0.56) | USP2SMN1; SMN2HPGDRECQLGPR119 | |
| Water SCHEMBL27687949 | 0.77 | USP2 (0.51) | USP2SMN1; SMN2HPGDRECQLGPR119 | |
| SCHEMBL27902866 | 0.77 | HPGD (0.58) | USP2SMN1; SMN2HPGDRECQLSTS | |
| SCHEMBL23487060 | 0.76 | USP2 (0.46) | USP2SMN1; SMN2HPGDSTSGPR119 | |
| SCHEMBL5572609 | 0.76 | USP2 (0.46) | USP2SMN1; SMN2HPGDSTSGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135659-B | Morpholine derivative, and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-115135659-A | Morpholine derivatives and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-09-30 | — | — | CN | disclosed |
| WO-2022152229-A1 | CLASS OF MORPHOLINE DERIVATIVES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-07-21 | — | — | WO | disclosed |