Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | HCK | P08631 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3339983 | 0.78 | PIK3CA (0.38) | HTR6L3MBTL1BUB1AKT1HSP90AA1 | |
| SCHEMBL28880984 | 0.75 | BUB1 (0.34) | HTR6L3MBTL1BUB1AKT1HSP90AA1 | |
| SCHEMBL17113072 | 0.75 | UCHL1 (0.41) | HTR6L3MBTL1BUB1PIK3CAPIK3R1 | |
| SCHEMBL29507058 | 0.73 | L3MBTL1 (0.44) | HTR6L3MBTL1BUB1AKT1HSP90AA1 | |
| SCHEMBL1284244 | 0.73 | L3MBTL1 (0.44) | HTR6L3MBTL1BUB1AKT1HSP90AA1 | |
| SCHEMBL14029835 | 0.72 | L3MBTL1 (0.40) | HTR6L3MBTL1BUB1AKT1HSP90AA1 | |
| SCHEMBL25338447 | 0.72 | ACHE (0.43) | — | |
| SCHEMBL2127172 | 0.71 | BUB1 (0.38) | HTR6L3MBTL1BUB1AKT1HSP90AA1 | |
| SCHEMBL29830789 | 0.71 | BUB1 (0.38) | HTR6L3MBTL1BUB1AKT1HSP90AA1 | |
| SCHEMBL26683889 | 0.71 | BUB1 (0.38) | HTR6L3MBTL1BUB1AKT1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135659-B | Morpholine derivative, and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-115135659-A | Morpholine derivatives and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-09-30 | — | — | CN | disclosed |
| WO-2022152229-A1 | CLASS OF MORPHOLINE DERIVATIVES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-07-21 | — | — | WO | disclosed |