Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29674195 | 0.92 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL22687312 | 0.91 | P2RX7 (0.31) | — | |
| SCHEMBL19638707 | 0.85 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL28412942 | 0.84 | MAPK1 (0.30) | MAPK1 | |
| SCHEMBL25199539 | 0.83 | JAK1 (0.32) | — | |
| SCHEMBL3476918 | 0.77 | — | — | |
| SCHEMBL22760036 | 0.74 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL28624786 | 0.70 | CA1 (0.32) | — | |
| SCHEMBL3786184 | 0.70 | DAO (0.33) | — | |
| SCHEMBL140519 | 0.70 | LPL (0.32) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4572755-A2 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024039901-A2 | CDK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |
| CN-110713489-B | Heteroaryl SYK inhibitors | 勃林格殷格翰国际有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-110183440-B | Heteroaryl SYK inhibitors | 勃林格殷格翰国际有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-114008036-A | Disubstituted pyrazole compounds as ketohexokinase inhibitors | 伊莱利利公司 | 2022-02-01 | — | — | CN | disclosed |
| CN-110862390-A | Fused tricyclic compound and application thereof in medicines | 广东东阳光药业有限公司 | 2020-03-06 | — | — | CN | disclosed |
| CN-110713489-A | Heteroaryl SYK inhibitors | 勃林格殷格翰国际有限公司 | 2020-01-21 | — | — | CN | disclosed |