Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17869112 | 0.81 | ESR1 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2235142 | 0.81 | PDE4B (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30230119 | 0.72 | L3MBTL1 (0.54) | MEN1LMNAKMT2AGAAKDM4E | |
| SCHEMBL25355195 | 0.71 | KDM4E (0.47) | MEN1LMNATP53KMT2AHSD17B10 | |
| SCHEMBL2233139 | 0.71 | GRM2 (0.38) | PDE4BMEN1KMT2AKDM4EGRM2 | |
| SCHEMBL18049818 | 0.71 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1546951 | 0.70 | KMT2A (0.57) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9364620 | 0.70 | LMNA (0.51) | MEN1LMNAKMT2AHSD17B10MAPT | |
| SCHEMBL15268626 | 0.70 | PTGS2 (0.61) | PDE4BMEN1TP53KMT2AHSD17B10 | |
| SCHEMBL19362950 | 0.69 | PDE4B (0.58) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406451-B | Pyrrolopyrimidines and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors | 福马治疗股份有限公司 | 2019-12-17 | — | — | CN | disclosed |