Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14677024 | 1.00 | RAB9A (0.41) | RAB9ANPC1ALDH1A1HPGDHTT | |
| SCHEMBL28040521 | 0.87 | RAB9A (0.44) | RAB9ANPC1ALDH1A1HPGDHTT | |
| SCHEMBL9359645 | 0.87 | ERCC5 (0.46) | RAB9ANPC1ALDH1A1HPGDHTT | |
| SCHEMBL9359661 | 0.87 | ERCC5 (0.46) | RAB9ANPC1ALDH1A1HPGDHTT | |
| SCHEMBL5086043 | 0.86 | ALDH1A1 (0.41) | RAB9ANPC1ALDH1A1HPGDLMNA | |
| SCHEMBL9360083 | 0.80 | GAA (0.48) | RAB9ANPC1ALDH1A1HTTLMNA | |
| SCHEMBL9360085 | 0.80 | GAA (0.48) | RAB9ANPC1ALDH1A1HTTLMNA | |
| SCHEMBL28040524 | 0.79 | KDM4E (0.55) | NPC1ALDH1A1HPGDHTTLMNA | |
| SCHEMBL29216340 | 0.79 | RAB9A (0.46) | RAB9ANPC1ALDH1A1HPGDHTT | |
| SCHEMBL6473037 | 0.79 | KMT2A (0.49) | RAB9ANPC1ALDH1A1HPGDMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110713459-A | Design synthesis and application of quinolinone fumaramide derivatives | 西南大学 | 2020-01-21 | — | — | CN | disclosed |