SCHEMBL28040524

SCHEMBL28040524

NC(=O)/C=C(\C(N)=O)c1ccccc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.55
HPGD P15428 7/20 0.55
MAPT P10636 5/20 0.55
ALDH1A1 P00352 4/20 0.55
HSD17B10 Q99714 3/20 0.55
TSHR P16473 2/20 0.55
SMN1; SMN2 Q16637 4/20 0.47
CA1 P00915 2/20 0.47
CA9 Q16790 2/20 0.47
CA12 O43570 1/20 0.47
CA2 P00918 1/20 0.47
HMGB1 P09429 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CA7 P43166 1/20 0.47
NAPRT Q6XQN6 1/20 0.47
CA14 Q9ULX7 1/20 0.47
CYP3A4 P08684 2/20 0.44
GAA P10253 2/20 0.42
MPO P05164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5086043 0.88 ALDH1A1 (0.41) KDM4EHPGDMAPTALDH1A1HSD17B10
SCHEMBL8397874 0.87 HPGD (0.53) KDM4EHPGDMAPTALDH1A1HSD17B10
SCHEMBL8397869 0.87 HPGD (0.53) KDM4EHPGDMAPTALDH1A1HSD17B10
SCHEMBL14677024 0.79 RAB9A (0.41) HPGDALDH1A1SMN1; SMN2LMNAHTT
SCHEMBL28884331 0.79 RAB9A (0.41) HPGDALDH1A1SMN1; SMN2LMNAHTT
SCHEMBL27962196 0.79 CES2 (0.50) HPGDMAPTALDH1A1TSHRSMN1; SMN2
SCHEMBL14677359 0.77 CLCN2 (0.37) KDM4EMAPTALDH1A1HSD17B10TSHR
SCHEMBL27657952 0.77 CYP1A2 (0.60) KDM4EHPGDMAPTALDH1A1HSD17B10
SCHEMBL28100885 0.77 CLCN2 (0.37) KDM4EMAPTALDH1A1HSD17B10TSHR
SCHEMBL27589201 0.75 CTSD (0.51) HPGDMAPTALDH1A1SMN1; SMN2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104977808-A Black photosensitive resin composite and black matrix made from the black photosensitive resin composite DONGWOO FINE CHEM CO LTD 2015-10-14 CN disclosed