Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139339 | 0.88 | HPGD (0.48) | USP2SMN1; SMN2RECQLGRM5GPR119 | |
| SCHEMBL20645659 | 0.81 | USP2 (0.46) | USP2SMN1; SMN2GRM5GPR119RAB9A | |
| SCHEMBL344191 | 0.79 | SMN1; SMN2 (0.96) | USP2SMN1; SMN2RECQLGPR119RAB9A | |
| SCHEMBL20448044 | 0.78 | SMN1; SMN2 (1.00) | USP2SMN1; SMN2RECQLGPR119RAB9A | |
| SCHEMBL24673913 | 0.77 | USP2 (0.51) | USP2SMN1; SMN2RECQLGRM5GPR119 | |
| SCHEMBL10253506 | 0.77 | USP2 (0.51) | USP2SMN1; SMN2RECQLGRM5GPR119 | |
| SCHEMBL30897992 | 0.75 | USP2 (0.50) | USP2SMN1; SMN2RECQLGRM5GPR119 | |
| SCHEMBL513246 | 0.75 | USP2 (0.50) | USP2SMN1; SMN2RECQLGRM5GPR119 | |
| Acetic Acid SCHEMBL29118271 | 0.75 | SMN1; SMN2 (0.86) | USP2SMN1; SMN2RECQLGPR119RAB9A | |
| SCHEMBL2948300 | 0.74 | USP2 (0.49) | USP2SMN1; SMN2RECQLGRM5GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440507-B | Compound as apoptosis protein inhibitor and application thereof | 南京圣和药物研发有限公司 | 2022-10-18 | — | — | CN | disclosed |