Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228779 | 0.84 | NPC1 (0.72) | NPC1L3MBTL1HSD11B1MAOBMAOA | |
| SCHEMBL31228704 | 0.84 | NPC1 (0.72) | NPC1L3MBTL1HSD11B1MAOBMAOA | |
| SCHEMBL28501196 | 0.84 | NPC1 (0.72) | NPC1L3MBTL1MAOBMAOATRPM8 | |
| SCHEMBL28375634 | 0.84 | ALDH1A1 (0.54) | NPC1L3MBTL1HSD11B1TNFRSF1ATRPA1 | |
| SCHEMBL28514351 | 0.83 | NPC1 (0.70) | NPC1L3MBTL1MAOBMAOATRPM8 | |
| SCHEMBL7245709 | 0.83 | L3MBTL1 (0.70) | NPC1L3MBTL1MAOBMAOATRPM8 | |
| SCHEMBL7245706 | 0.83 | L3MBTL1 (0.70) | NPC1L3MBTL1MAOBMAOATRPM8 | |
| N,N-Diethylcinnamamide SCHEMBL23550023 | 0.82 | NPC1 (1.00) | NPC1L3MBTL1TRPM8LTB4RLTB4R2 | |
| N,N-Diethylcinnamamide SCHEMBL4956221 | 0.82 | NPC1 (1.00) | NPC1L3MBTL1TRPM8LTB4RLTB4R2 | |
| N,N-Diethylcinnamamide SCHEMBL4956226 | 0.82 | NPC1 (1.00) | NPC1L3MBTL1TRPM8LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111018735-B | Preparation method of cinnamamide compound | 河南农业大学 | 2021-09-07 | — | — | CN | disclosed |
| CN-111018735-A | Preparation method of cinnamamide | 河南农业大学 | 2020-04-17 | — | — | CN | disclosed |