Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | BRD2 | P25440 | 1/20 | 0.51 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.51 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28377022 | 0.82 | RAB9A (0.65) | MAPTHDAC1HDAC6HDAC11POLB | |
| SCHEMBL28377747 | 0.82 | MAPT (0.67) | MAPTHDAC1HDAC6POLBRXFP1 | |
| SCHEMBL28380865 | 0.82 | MAPT (0.79) | MAPTHDAC6POLBRXFP1SMN1; SMN2 | |
| SCHEMBL28377311 | 0.78 | HDAC1 (0.56) | MAPTHDAC1HDAC6HDAC11POLB | |
| SCHEMBL28383667 | 0.78 | ALDH1A1 (0.52) | MAPTHDAC1HDAC6HDAC11POLB | |
| SCHEMBL28381789 | 0.78 | RXFP1 (0.65) | MAPTPOLBRXFP1SMN1; SMN2RAB9A | |
| SCHEMBL28377019 | 0.78 | POLB (0.65) | MAPTPOLBRXFP1SMN1; SMN2RAB9A | |
| SCHEMBL28381515 | 0.77 | KDM4E (0.58) | MAPTHDAC1HDAC6HDAC11POLB | |
| SCHEMBL28377067 | 0.77 | POLB (0.62) | MAPTHDAC1HDAC6HDAC11POLB | |
| SCHEMBL28380664 | 0.76 | BRD4 (0.65) | MAPTHDAC1HDAC6HDAC11POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110938055-A | Six-membered ring formamide compound and synthesis method and application thereof | 华东师范大学 | 2020-03-31 | — | — | CN | claimed |
| CN-110938055-A | Six-membered ring formamide compound and synthesis method and application thereof | 华东师范大学 | 2020-03-31 | — | — | CN | disclosed |