Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL28889094

O=C1CCC(=O)CC1.OCCOCCO

nearest known ligand 0.56

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
MAPK1 P28482 1/20 0.56
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
ALDH1A1 P00352 3/20 0.39
MAPT P10636 3/20 0.36
THRB P10828 1/20 0.36
HTT P42858 1/20 0.36
TRIM24 O15164 2/20 0.33
TRIM33 Q9UPN9 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexanone SCHEMBL28125250 0.87 ALDH1A1 (0.52) TSHRMAPK1MEN1KMT2AALDH1A1
Ethylene Glycol SCHEMBL3420867 0.78 TRIM24 (0.44) TSHRKMT2AALDH1A1TRIM24TRIM33
Succinimide SCHEMBL28503670 0.77 CRBN (0.52) TSHRMAPK1MEN1KMT2AALDH1A1
Butoxyethanol SCHEMBL23121479 0.76 TSHR (0.61) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL22543431 0.75 MGLL (0.45) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL1462 0.74
Di(Hydroxyethyl)Ether SCHEMBL2410410 0.74 TSHR (1.00) TSHRMAPK1MEN1KMT2AALDH1A1
Ethylene Glycol SCHEMBL3420865 0.73 TRIM24 (0.39) TSHRALDH1A1TRIM24TRIM33
Di(Hydroxyethyl)Ether SCHEMBL7805707 0.72 TSHR (0.77) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL5213209 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115215832-B Preparation method of 1,4-cyclohexanedione mono ketal 无锡科华生物科技有限公司 2023-06-23 CN disclosed
CN-115215832-A Preparation method of 1,4-cyclohexanedione mono-ketal 无锡科华生物科技有限公司 2022-10-21 CN disclosed