Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 2/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893656 | 1.00 | MEN1 (0.43) | MEN1KMT2AADRB2POLBALDH1A1 | |
| SCHEMBL28889297 | 0.90 | ADRB2 (0.37) | MEN1KMT2AADRB2POLBALDH1A1 | |
| SCHEMBL29893817 | 0.90 | ADRB2 (0.37) | MEN1KMT2AADRB2POLBALDH1A1 | |
| SCHEMBL28889250 | 0.88 | MEN1 (0.44) | MEN1KMT2AADRB2POLBALDH1A1 | |
| SCHEMBL29893755 | 0.88 | MEN1 (0.44) | MEN1KMT2AADRB2POLBALDH1A1 | |
| SCHEMBL28889186 | 0.88 | MEN1 (0.44) | MEN1KMT2AADRB2POLBALDH1A1 | |
| SCHEMBL29941697 | 0.88 | MEN1 (0.49) | MEN1KMT2AADRB2POLBALDH1A1 | |
| SCHEMBL28889213 | 0.83 | ADRB2 (0.41) | MEN1KMT2AADRB2ALDH1A1L3MBTL1 | |
| SCHEMBL28959166 | 0.82 | MEN1 (0.41) | MEN1KMT2AADRB2POLBLMNA | |
| SCHEMBL28889280 | 0.81 | AURKA (0.40) | ADRB2AURKACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |