Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 2/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 5/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | TNNI3K | Q59H18 | 4/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941767 | 0.89 | ADRB2 (0.39) | MEN1KMT2AADRB2LMNAP2RY1 | |
| SCHEMBL28889179 | 0.89 | KMT2A (0.41) | MEN1KMT2AADRB2LMNAP2RY1 | |
| SCHEMBL28889178 | 0.88 | HDAC4 (0.43) | MEN1KMT2AADRB2LMNAP2RY1 | |
| SCHEMBL29941978 | 0.85 | MEN1 (0.40) | MEN1KMT2AADRB2LMNARIPK2 | |
| SCHEMBL29893755 | 0.85 | MEN1 (0.44) | MEN1KMT2AADRB2LMNAP2RY1 | |
| SCHEMBL28889250 | 0.85 | MEN1 (0.44) | MEN1KMT2AADRB2LMNAP2RY1 | |
| SCHEMBL29941697 | 0.84 | MEN1 (0.49) | MEN1KMT2AADRB2POLBCHIT1 | |
| SCHEMBL28889186 | 0.83 | MEN1 (0.44) | MEN1KMT2AADRB2LMNAP2RY1 | |
| SCHEMBL29893656 | 0.82 | MEN1 (0.43) | MEN1KMT2AADRB2LMNAPOLB | |
| SCHEMBL28889281 | 0.81 | KMT2A (0.40) | MEN1KMT2AADRB2LMNAP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |