Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28959159 | 0.90 | ADRB2 (0.38) | ADRB2ALDH1A1L3MBTL1GAAEPAS1 | |
| SCHEMBL28889336 | 0.90 | HDAC4 (0.41) | ADRB2CTSAALDH1A1L3MBTL1TRPV3 | |
| SCHEMBL28889204 | 0.89 | ADRB2 (0.39) | ADRB2ALDH1A1L3MBTL1EPAS1LMNA | |
| SCHEMBL28889284 | 0.89 | ADRB2 (0.37) | ADRB2ALDH1A1L3MBTL1GAATRPV3 | |
| SCHEMBL29893753 | 0.89 | ADRB2 (0.37) | ADRB2ALDH1A1L3MBTL1GAATRPV3 | |
| SCHEMBL28889187 | 0.84 | MEN1 (0.40) | ADRB2CTSAALDH1A1L3MBTL1GAA | |
| SCHEMBL28889237 | 0.83 | ADRB2 (0.39) | ADRB2ALDH1A1L3MBTL1GAASORT1 | |
| SCHEMBL28889194 | 0.83 | ADRB2 (0.37) | ADRB2ALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL29941794 | 0.82 | ADRB2 (0.38) | ADRB2CTSAALDH1A1L3MBTL1GAA | |
| SCHEMBL28889339 | 0.80 | ADRB2 (0.42) | ADRB2CTSAALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |