Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28889194 | 0.89 | ADRB2 (0.37) | ADRB2SORT1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL29894640 | 0.85 | HDAC4 (0.40) | ADRB2ALDH1A1L3MBTL1MAPTP2RY1 | |
| SCHEMBL28889386 | 0.85 | HDAC4 (0.40) | ADRB2ALDH1A1L3MBTL1MAPTP2RY1 | |
| SCHEMBL28889213 | 0.84 | ADRB2 (0.41) | ADRB2ACACBSORT1ALDH1A1GAA | |
| SCHEMBL28889308 | 0.83 | ADRB2 (0.38) | ADRB2SORT1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL29893753 | 0.82 | ADRB2 (0.37) | ADRB2SORT1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL28889284 | 0.82 | ADRB2 (0.37) | ADRB2SORT1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL29942364 | 0.82 | ADRB2 (0.40) | ADRB2ACACBSORT1ALDH1A1GAA | |
| SCHEMBL28959159 | 0.81 | ADRB2 (0.38) | ADRB2ALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL28889336 | 0.81 | HDAC4 (0.41) | ADRB2ALDH1A1L3MBTL1P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |