Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 13/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28889308 | 0.90 | ADRB2 (0.38) | ADRB2TRPV3ALDH1A1L3MBTL1LMNA | |
| SCHEMBL28959159 | 0.90 | ADRB2 (0.38) | HDAC4HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL28889204 | 0.89 | ADRB2 (0.39) | ADRB2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL29893753 | 0.87 | ADRB2 (0.37) | ADRB2P2RY1TRPV3ALDH1A1L3MBTL1 | |
| SCHEMBL28889284 | 0.87 | ADRB2 (0.37) | ADRB2P2RY1TRPV3ALDH1A1L3MBTL1 | |
| SCHEMBL28889178 | 0.84 | HDAC4 (0.43) | HDAC4HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL29894640 | 0.83 | HDAC4 (0.40) | HDAC4HDAC7HDAC5ADRB2P2RY1 | |
| SCHEMBL28889386 | 0.83 | HDAC4 (0.40) | HDAC4HDAC7HDAC5ADRB2P2RY1 | |
| SCHEMBL29941803 | 0.82 | HDAC4 (0.42) | HDAC4HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL28889237 | 0.81 | ADRB2 (0.39) | ADRB2P2RY1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |