Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941911 | 0.92 | MEN1 (0.43) | MEN1KMT2APOLBALDH1A1CYP1A2 | |
| SCHEMBL28889200 | 0.86 | ADRB2 (0.41) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL29941823 | 0.82 | ADRB2 (0.40) | MEN1KMT2APOLBALDH1A1CYP1A2 | |
| SCHEMBL28889152 | 0.81 | ADRB2 (0.37) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL29893979 | 0.80 | ADRB2 (0.38) | MEN1KMT2APOLBALDH1A1CYP1A2 | |
| SCHEMBL28889154 | 0.79 | ADRB2 (0.38) | MEN1KMT2APOLBALDH1A1CYP1A2 | |
| SCHEMBL28889330 | 0.78 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL29893684 | 0.78 | ADRB2 (0.39) | MEN1KMT2APOLBALDH1A1CYP1A2 | |
| SCHEMBL28889286 | 0.78 | ADRB2 (0.36) | MEN1KMT2APOLBALDH1A1CYP1A2 | |
| SCHEMBL28889188 | 0.77 | ADRB2 (0.39) | MEN1KMT2APOLBALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |