Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28889177 | 0.96 | HDAC4 (0.40) | LMNAHDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL29941747 | 0.91 | EPHX2 (0.41) | LMNAHDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL29893626 | 0.90 | LMNA (0.41) | LMNAKMT2AMEN1NPSR1GALR3 | |
| SCHEMBL28889248 | 0.90 | LMNA (0.41) | LMNAKMT2AMEN1NPSR1GALR3 | |
| SCHEMBL29942164 | 0.87 | HDAC4 (0.41) | HDAC4HDAC3HDAC1HDAC7HDAC8 | |
| SCHEMBL28889330 | 0.86 | ALDH1A1 (0.44) | LMNAKMT2AMEN1NPSR1PHGDH | |
| SCHEMBL28889234 | 0.86 | PDE4B (0.38) | LMNAKMT2ANPSR1HTTPHGDH | |
| SCHEMBL29893652 | 0.86 | PDE4B (0.38) | LMNAKMT2ANPSR1HTTPHGDH | |
| SCHEMBL29941803 | 0.85 | HDAC4 (0.42) | LMNAHDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL28889299 | 0.82 | HDAC4 (0.40) | LMNAHDAC4HDAC3HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |