Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893626 | 1.00 | LMNA (0.41) | LMNAKMT2ANPSR1GALR3PHGDH | |
| SCHEMBL29893652 | 0.96 | PDE4B (0.38) | LMNAKMT2ANPSR1PHGDHHTT | |
| SCHEMBL28889234 | 0.96 | PDE4B (0.38) | LMNAKMT2ANPSR1PHGDHHTT | |
| SCHEMBL28889338 | 0.90 | LMNA (0.41) | LMNAKMT2ANPSR1GALR3PHGDH | |
| SCHEMBL28889177 | 0.86 | HDAC4 (0.40) | LMNAKMT2ANPSR1PHGDHMEN1 | |
| SCHEMBL28889330 | 0.83 | ALDH1A1 (0.44) | LMNAKMT2ANPSR1PHGDHMEN1 | |
| SCHEMBL29941747 | 0.81 | EPHX2 (0.41) | LMNAKMT2ASMN1; SMN2MEN1EPHX2 | |
| SCHEMBL28889343 | 0.80 | HCRTR1 (0.42) | LMNAKMT2ANPSR1PHGDHALDH1A1 | |
| SCHEMBL28889290 | 0.79 | LMNA (0.40) | LMNAKMT2ANPSR1GALR3PHGDH | |
| SCHEMBL28889357 | 0.79 | ALDH1A1 (0.39) | LMNAKMT2ANPSR1GALR3PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |