SCHEMBL28889391

SCHEMBL28889391

Nc1ccc(C(=O)OC(=O)CC[C@@H](N)C(=O)OC(=O)c2ccc(N)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
CYP1A2 P05177 3/20 0.46
CYP3A4 P08684 3/20 0.46
MAOA P21397 2/20 0.46
TSHR P16473 2/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
PDE4D Q08499 1/20 0.42
PHLPP2 Q6ZVD8 1/20 0.41
SCN1A P35498 2/20 0.40
SCN2A Q99250 2/20 0.40
SCN3A Q9NY46 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
MAPT P10636 2/20 0.40
ALDH1A1 P00352 1/20 0.40
ADRB2 P07550 2/20 0.40
ADRB1 P08588 2/20 0.40
ADRB3 P13945 2/20 0.40
CYP2D6 P10635 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1232253 1.00 LMNA (0.46) LMNACYP1A2CYP3A4MAOATSHR
SCHEMBL5078447 1.00 LMNA (0.46) LMNACYP1A2CYP3A4MAOATSHR
SCHEMBL5078448 0.88 CYP1A2 (0.46) LMNACYP1A2CYP3A4MAOATSHR
SCHEMBL21291549 0.88 CYP1A2 (0.46) LMNACYP1A2CYP3A4MAOATSHR
SCHEMBL5084405 0.86 ALDH1A1 (0.44) LMNATSHRMAPTALDH1A1GAA
SCHEMBL5084403 0.86 ALDH1A1 (0.44) LMNATSHRMAPTALDH1A1GAA
SCHEMBL28889387 0.85 LMNA (0.41) LMNACYP1A2CYP3A4MAOATSHR
SCHEMBL28889389 0.85 LMNA (0.44) LMNACYP1A2CYP3A4MAOATSHR
SCHEMBL28889419 0.85 LMNA (0.41) LMNACYP1A2CYP3A4MAOATSHR
Hydrochloric Acid SCHEMBL31375791 0.85 ALDH1A1 (0.42) LMNATSHRMAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115368262-A Preparation method of folic acid key intermediate 衡阳小桔制药有限公司 2022-11-22 CN claimed
CN-115368262-A Preparation method of folic acid key intermediate 衡阳小桔制药有限公司 2022-11-22 CN disclosed
CN-115368262-A Preparation method of folic acid key intermediate 衡阳小桔制药有限公司 2022-11-22 CN disclosed