Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 8/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28402124 | 0.83 | RAB9A (0.56) | RAB9ANPC1KDM4EMAPTPKM | |
| SCHEMBL28889673 | 0.81 | RAB9A (0.45) | RAB9ANPC1KDM4EMAPTPKM | |
| SCHEMBL28401383 | 0.81 | RAB9A (0.45) | RAB9ANPC1KDM4EMAPTPKM | |
| SCHEMBL28398018 | 0.80 | RAB9A (0.52) | RAB9ANPC1KDM4EMAPTPKM | |
| SCHEMBL28402025 | 0.80 | TLR9 (0.53) | RAB9ANPC1KDM4EMAPTPKM | |
| SCHEMBL28406931 | 0.78 | RAB9A (0.38) | RAB9ANPC1KDM4EMAPTPKM | |
| SCHEMBL28396792 | 0.77 | TLR9 (0.61) | RAB9ANPC1KDM4EPKMTLR9 | |
| SCHEMBL17492276 | 0.77 | RAB9A (0.44) | RAB9ANPC1KDM4EMAPTPKM | |
| SCHEMBL30138150 | 0.77 | RAB9A (0.44) | RAB9ANPC1KDM4EMAPTPKM | |
| SCHEMBL1691818 | 0.76 | LMNA (0.53) | RAB9ANPC1KDM4EMAPTSUV39H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776574-B | Bis (2- (imidazo [1,2-a ] pyridine-2-yl) phenyl) thioether compound and synthetic method thereof | 郑州大学 | 2020-04-28 | — | — | CN | disclosed |