Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 6/20 | 0.43 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851742 | 0.91 | KDM4E (0.58) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL4914225 | 0.87 | KDM4E (0.46) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL27437528 | 0.83 | KDM4E (0.46) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL203438 | 0.83 | GSK3B (0.49) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL14797167 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL6784000 | 0.82 | KDM4E (0.56) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL861495 | 0.81 | PTPN2 (0.54) | ALDH1A1HPGDMAPTHSD17B10GAA | |
| SCHEMBL16702560 | 0.80 | KDM4E (0.41) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL18094286 | 0.80 | KDM4E (0.41) | ALDH1A1HPGDMAPTKDM4EHSD17B10 | |
| SCHEMBL31521444 | 0.80 | NOTUM (0.53) | ALDH1A1HPGDMAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286215-A1 | BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | 2010-11-11 | — | — | US | disclosed |
| EP-2185504-A2 | BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009030887-A2 | BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2009-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286215-A1 | BIS-AROMATIC COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | LTC4S, LTB4R2, LTB4R | ALDH1A1 760/4885HPGD 366/4885MAPT 3432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.