SCHEMBL28890215

SCHEMBL28890215

COc1ccc(-c2ccc(OC)cc2)cc1.COc1ccc(-c2ccc(OC)cc2)cc1.SS

nearest known ligand 0.93

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.73
CA2 P00918 2/20 0.73
CA7 P43166 2/20 0.73
CA9 Q16790 2/20 0.73
CA12 O43570 1/20 0.73
CA14 Q9ULX7 1/20 0.73
ESR2 Q92731 1/20 0.70
MAPK1 P28482 3/20 0.61
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
TP53 P04637 2/20 0.61
CASP3 P42574 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
SENP8 Q96LD8 1/20 0.61
SENP7 Q9BQF6 1/20 0.61
SENP6 Q9GZR1 1/20 0.61
APP P05067 1/20 0.59
ACHE P22303 1/20 0.58
MAOB P27338 2/20 0.56
ABL1 P00519 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197522 0.97 CA1 (0.79) CA1CA2CA7CA9CA12
SCHEMBL6733562 0.97 CA1 (0.79) CA1CA2CA7CA9CA12
SCHEMBL9151672 0.97 CA1 (0.79) CA1CA2CA7CA9CA12
Methyl Alcohol SCHEMBL28098026 0.90 ESR2 (0.75) CA1CA2CA7CA9CA12
SCHEMBL7243101 0.89 ESR2 (0.58) CA1CA2CA7CA9CA12
SCHEMBL13038584 0.88 LTA4H (0.67) CA1CA2CA7CA9CA12
SCHEMBL7610770 0.88 LTA4H (0.67) CA1CA2CA7CA9CA12
SCHEMBL3743494 0.88 ABL1 (0.71) CA1CA2CA7CA9CA12
SCHEMBL920933 0.88 ABL1 (0.71) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL8489 0.86 CA1 (1.00) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112390697-B Synthesis method of N-arylselenium/thioethyl sulfoxide imine 成都理工大学 2023-03-10 CN claimed
CN-112390697-A Synthesis method of N-arylselenium/thioethyl sulfoxide imine 成都理工大学 2021-02-23 CN claimed
CN-118221642-A Sulfonamide derivative and application thereof in medicine 西藏海思科制药有限公司 2024-06-21 CN disclosed
CN-117924411-A Method for thioimidization of amino acid or polypeptide carboxyl locus and application of method in preparation of antitumor polypeptide coupling medicine 兰州大学 2024-04-26 CN disclosed
CN-117802511-A Preparation method of thiosulfate compound 西华大学 2024-04-02 CN disclosed
CN-116284676-A High Jiang Zixiu complex ion gel and preparation method thereof 东华大学 2023-06-23 CN disclosed
CN-109836364-B Method for continuously producing aryl disulfide compound in pipeline manner 浙江大学 2020-06-02 CN disclosed