SCHEMBL28890273

SCHEMBL28890273

CCCc1cc(Br)c(C#N)c(C#N)c1Br

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
HPGD P15428 3/20 0.35
CYP1A2 P05177 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KDM4E B2RXH2 4/20 0.33
GAA P10253 3/20 0.33
GLA P06280 2/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPK1 P28482 1/20 0.32
RECQL P46063 1/20 0.32
MME P08473 1/20 0.31
AR P10275 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28889526 0.75 ALDH1A1 (0.37) ALDH1A1HPGDCYP1A2HSD17B10KDM4E
SCHEMBL7608134 0.71 TDP1 (0.36) MAPT
SCHEMBL11481364 0.71 MEN1 (0.36) HTTMEN1KMT2A
SCHEMBL23893065 0.70 KDM4E (0.32) ALDH1A1HPGDCYP1A2HSD17B10KDM4E
SCHEMBL23610900 0.70 CA1 (0.35)
SCHEMBL26707584 0.70 HMGCR (0.37) ALDH1A1HPGDHSD17B10KDM4EHTT
SCHEMBL28654378 0.69 ALDH1A1 (0.39) ALDH1A1HPGDCYP1A2HSD17B10KDM4E
SCHEMBL25188943 0.67 CTSK (0.37) ALDH1A1HPGDHSD17B10KDM4EMEN1
SCHEMBL30403137 0.67 CTSK (0.37) ALDH1A1HPGDHSD17B10KDM4EMEN1
SCHEMBL4773225 0.67 MEN1 (0.43) ALDH1A1HSD17B10MEN1KMT2ACTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112955302-B Method for manufacturing a laminate with partial curing 斯特拉塔西斯公司 2023-05-02 CN disclosed
CN-115943062-A Dual cure additive manufacturing resin for producing flame retardant objects 卡本有限公司 2023-04-07 CN disclosed
CN-112930257-B Three-dimensional inkjet printing of thermally stable objects 斯特拉塔西斯公司 2023-03-24 CN disclosed
CN-112955302-A Method for build-up manufacturing with partial curing 斯特拉塔西斯公司 2021-06-11 CN disclosed
CN-112930257-A Three-dimensional inkjet printing of thermally stable objects 斯特拉塔西斯公司 2021-06-08 CN disclosed
CN-111107975-A Resin composition, method for producing three-dimensional object using same, three-dimensional object, fitting for holding object, and industrial robot using same 柯尼卡美能达株式会社 2020-05-05 CN disclosed