Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | CCR8 | P51685 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958311 | 1.00 | KCNMA1 (0.41) | KCNMA1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL30101789 | 0.76 | KMT2A (0.36) | KDM4EALDH1A1KMT2AMEN1POLB | |
| SCHEMBL22275064 | 0.76 | KMT2A (0.36) | KDM4EALDH1A1KMT2AMEN1POLB | |
| SCHEMBL7435562 | 0.74 | PRMT5 (0.46) | KDM4EALDH1A1HPGDTDP1PRMT5 | |
| SCHEMBL1163209 | 0.74 | ALDH1A1 (0.60) | KDM4EALDH1A1KMT2AMEN1POLB | |
| SCHEMBL29799045 | 0.74 | ALDH1A1 (0.60) | KDM4EALDH1A1KMT2AMEN1POLB | |
| SCHEMBL4847216 | 0.73 | ALDH1A1 (0.38) | KCNMA1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10000604 | 0.72 | KCNMA1 (0.42) | KCNMA1KDM4EALDH1A1KMT2ATDP1 | |
| SCHEMBL6646968 | 0.71 | KDM4E (0.39) | KCNMA1KDM4EALDH1A1POLBHPGD | |
| SCHEMBL24063471 | 0.70 | HTT (0.43) | KDM4EALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362155-B | Arylamine derivative, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-115362155-A | Arylamine derivatives, and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2022-11-18 | — | — | CN | disclosed |