Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN3 | Q9UGI6 | 14/20 | 0.54 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.48 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29236251 | 1.00 | KCNN3 (0.54) | KCNN3KCNN1KCNN2PDE10ACRHR1 | |
| SCHEMBL28890496 | 0.87 | TLR8 (0.43) | KCNN3CRHR1TLR8TLR7 | |
| SCHEMBL19526824 | 0.76 | KCNN3 (0.66) | KCNN3KCNN1KCNN2PDE10ACRHR1 | |
| SCHEMBL20220569 | 0.73 | KCNN3 (0.56) | KCNN3KCNN1KCNN2PDE10ACRHR1 | |
| SCHEMBL14158199 | 0.72 | PDE10A (0.61) | KCNN3KCNN1KCNN2PDE10A | |
| SCHEMBL1934962 | 0.70 | KCNN3 (0.58) | KCNN3KCNN1KCNN2PDE10A | |
| SCHEMBL13778075 | 0.68 | KCNN3 (0.65) | KCNN3KCNN1KCNN2PDE10ACRHR1 | |
| SCHEMBL5453937 | 0.66 | KCNN3 (0.53) | KCNN3KCNN1KCNN2PDE10A | |
| SCHEMBL13117302 | 0.65 | KCNN3 (0.80) | KCNN3KCNN1KCNN2PDE10A | |
| SCHEMBL10761854 | 0.65 | SMN1; SMN2 (0.46) | CRHR1TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362155-B | Arylamine derivative, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-115362155-A | Arylamine derivatives, and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2022-11-18 | — | — | CN | disclosed |