Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.58 |
| ▸ | HCAR3 | P49019 | 12/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28432435 | 0.98 | CASP6 (0.62) | CASP6TSHRLMNAVCAM1HCAR3 | |
| SCHEMBL23037538 | 0.97 | CASP6 (0.60) | CASP6TSHRLMNAVCAM1HCAR3 | |
| SCHEMBL15208519 | 0.87 | PARP1 (0.61) | CASP6TSHRLMNAVCAM1 | |
| SCHEMBL18113454 | 0.87 | CASP6 (0.64) | CASP6TSHRLMNAVCAM1HCAR3 | |
| SCHEMBL289572 | 0.85 | VCAM1 (0.61) | CASP6TSHRLMNAVCAM1APEX1 | |
| SCHEMBL12437546 | 0.85 | CASP6 (0.49) | CASP6TSHRLMNAVCAM1HCAR3 | |
| SCHEMBL9882428 | 0.85 | ALDH1A1 (0.48) | CASP6TSHRLMNAVCAM1HCAR3 | |
| SCHEMBL16953006 | 0.83 | VCAM1 (0.58) | CASP6TSHRLMNAVCAM1HCAR3 | |
| SCHEMBL28317899 | 0.83 | CASP6 (0.64) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL11702728 | 0.82 | VCAM1 (0.50) | CASP6TSHRLMNAVCAM1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114163347-B | Synthesis method of N-acyl glutamate | 镇江中智化学科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-116178301-A | Preparation method of cyclic lipopeptides natural product Dysoxyactam A and analogues thereof | 中国科学院上海药物研究所 | 2023-05-30 | — | — | CN | disclosed |
| CN-106242998-B | Use of 4-cyano-3-benzoylamino-N-phenyl-benzamides in pesticides | 先正达参股股份有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-111333545-B | 3, 6-dioxocyclohexyl-1, 4-diene-1, 2-dinitrile derivative, preparation and application thereof | 华中科技大学 | 2021-03-26 | — | — | CN | disclosed |
| EP-3786143-A1 | PROCESS FOR PREPARING FLUOROBENZENE DERIVATIVES AND BENZOIC ACID HYPOFLUORITE DERIVATIVES | Fujian Yongjing Technology Co., Ltd. (CN) | 2021-03-03 | — | — | EP | disclosed |
| CN-111423393-A | Synthetic method of seventeen-membered large cyclic lipopeptide natural compound | 北京大学深圳研究生院 | 2020-07-17 | — | — | CN | disclosed |
| CN-111333545-A | 3, 6-dioxocyclohexyl-1, 4-diene-1, 2-dinitrile derivative, preparation and application thereof | 华中科技大学 | 2020-06-26 | — | — | CN | disclosed |
| EP-2636667-B1 | BENZAMIDE DERIVATIVE WITH ANTICANCER ACTIVITY AND PREPARATION METHOD AND USE THEREOF | ZHEJIANG HISUN PHARM CO LTD (CN) | 2019-01-09 | — | — | EP | disclosed |
| US-10130633-B2 | Compounds | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-11-20 | — | — | US | disclosed |
| EP-2976327-B1 | 3-ACETYLAMINO-1-(PHENYL-HETEROARYL-AMINOCARBONYL OR PHENYL-HETEROARYL-CARBONYLAMINO)BENZENE DERIVATIVES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | Bayer Pharma AG (DE) | 2017-06-21 | — | — | EP | disclosed |
| EP-0579826-B1 | CARBAPENEMS CONTAINING A CARBOXY SUBSTITUTED PHENYL GROUP, PROCESSES FOR THEIR PREPARATION, INTERMEDIATES AND USE AS ANTIBIOTICS | ZENECA LTD (GB) | 1998-11-11 | — | — | EP | disclosed |
| US-5652233-A | CARBAPENICILLINS | ZENECA LIMITED (GB) | 1997-07-29 | — | — | US | disclosed |
| US-5478820-A | Carbapenem deivatives; bactericides | ZENECA LTD. (GB) | 1995-12-26 | — | — | US | disclosed |
| EP-0497765-B1 | PROCESS FOR THE PRODUCTION OF ORTHO-NITROBENZONITRILES | ICI AMERICA INC (US) | 1994-09-28 | — | — | EP | disclosed |
| EP-0579826-A1 | CARBAPENEMS CONTAINING A CARBOXY SUBSTITUTED PHENYL GROUP, PROCESSES FOR THEIR PREPARATION, INTERMEDIATES AND USE AS ANTIBIOTICS | ZENECA LIMITED (GB) | 1994-01-26 | — | — | EP | disclosed |
| WO-1993015078-A1 | CARBAPENEMS CONTAINING A CARBOXY SUBSTITUTED PHENYL GROUP, PROCESSES FOR THEIR PREPARATION, INTERMEDIATES AND USE AS ANTIBIOTICS | ZENECA LIMITED (GB) | 1993-08-05 | — | — | WO | disclosed |
| EP-0497765-A1 | PROCESS FOR THE PRODUCTION OF ORTHO-NITROBENZONITRILES. | ICI AMERICA INC (US) | 1992-08-12 | — | — | EP | disclosed |
| WO-1991006530-A1 | PROCESS FOR THE PRODUCTION OF ORTHO-NITROBENZONITRILES | ICI AMERICAS INC. (US) | 1991-05-16 | — | — | WO | disclosed |
| EP-0425743-A1 | Process for the production of ortho-nitrobenzonitriles | ICI AMERICAS INC. (US) | 1991-05-08 | — | — | EP | disclosed |
| US-4886936-A | REACTING ORTHONITROCHLOROBENZENE WITH (CUPROUS OR LITHIUM) CYANIDE AND BROMIDE | ICI AMERICAS INC. (US) | 1989-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10130633-B2 | Compounds | AADAC, NAT1, CBR3 | CASP6 1116/4885TSHR 2036/4885LMNA 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.