Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25155836 | 0.87 | — | — | |
| SCHEMBL29494522 | 0.87 | — | — | |
| SCHEMBL1321466 | 0.87 | — | — | |
| SCHEMBL29494539 | 0.82 | MEN1 (0.53) | MEN1KMT2A | |
| SCHEMBL28404707 | 0.82 | MEN1 (0.53) | MEN1KMT2A | |
| SCHEMBL29793667 | 0.82 | MEN1 (0.53) | MEN1KMT2A | |
| SCHEMBL28257375 | 0.82 | LMNA (0.61) | ALDH1A1MEN1KMT2A | |
| SCHEMBL10527020 | 0.82 | NPC1 (0.55) | MEN1KMT2A | |
| SCHEMBL10527016 | 0.82 | NPC1 (0.55) | MEN1KMT2A | |
| SCHEMBL7932004 | 0.82 | MEN1 (0.51) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929263-B | Arylamide Kv2.1 inhibitor and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-07-22 | — | — | CN | disclosed |
| CN-111108092-A | Arylamide Kv2.1 inhibitor and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2020-05-05 | — | — | CN | disclosed |