SCHEMBL28890787

SCHEMBL28890787

C=CC(=O)O[Si](OC(=O)C=C)(OC(=O)C=C)c1ccc(C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.42
ALDH1A1 P00352 9/20 0.35
HTT P42858 5/20 0.35
LMNA P02545 4/20 0.35
HPGD P15428 4/20 0.35
NPSR1 Q6W5P4 3/20 0.35
PKM P14618 2/20 0.35
ATM Q13315 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NLRP1 Q9C000 1/20 0.35
MEN1 O00255 1/20 0.35
NTSR1 P30989 1/20 0.35
KMT2A Q03164 1/20 0.35
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
THRB P10828 3/20 0.34
GSTO1 P78417 1/20 0.34
ACHE P22303 1/20 0.33
MAPT P10636 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28959321 0.81 THRB (0.43) TGM2ALDH1A1LMNAHPGDPKM
SCHEMBL27863591 0.77 THRB (0.38) TGM2ALDH1A1HPGDTDP1CES2
SCHEMBL6562707 0.76 LMNA (0.48) ALDH1A1HTTLMNAHPGDNPSR1
SCHEMBL28890782 0.76 LMNA (0.39) ALDH1A1HTTLMNAHPGDNPSR1
SCHEMBL2577761 0.75 THRB (0.39) TGM2ALDH1A1HTTLMNAHPGD
P-Xylene SCHEMBL27798321 0.74 TGM2 (0.53) TGM2ALDH1A1HTTLMNAHPGD
SCHEMBL39792 0.72 THRB (0.59) TGM2ALDH1A1HTTLMNAHPGD
SCHEMBL2579938 0.71 THRB (0.40) TGM2ALDH1A1HPGDMEN1KMT2A
Hydrochloric Acid SCHEMBL19749007 0.71 THRB (0.58) TGM2ALDH1A1HTTLMNAHPGD
SCHEMBL27701665 0.71 THRB (0.58) TGM2ALDH1A1HTTLMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106605309-B LED lamp, manufacturing method of LED lamp and sealing method of LED device 英克伦股份有限公司 2022-10-18 CN disclosed