SCHEMBL28891069

SCHEMBL28891069

O=C(NO)c1cc2ccccc2o1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.68
RAB9A P51151 8/20 0.68
TP53 P04637 5/20 0.68
SMN1; SMN2 Q16637 3/20 0.68
PKM P14618 2/20 0.68
NFKB1 P19838 1/20 0.68
NFKB2 Q00653 1/20 0.68
RELA Q04206 1/20 0.68
FLT3 P36888 1/20 0.67
ALDH1A1 P00352 3/20 0.64
HPGD P15428 1/20 0.64
MEN1 O00255 2/20 0.61
TSHR P16473 2/20 0.61
KMT2A Q03164 2/20 0.61
MAPK1 P28482 1/20 0.61
NLRP3 Q96P20 1/20 0.61
LMNA P02545 2/20 0.60
TAS1R3 Q7RTX0 1/20 0.60
TAS1R1 Q7RTX1 1/20 0.60
GALK1 P51570 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13485789 1.00 NPC1 (0.68) NPC1RAB9ATP53SMN1; SMN2PKM
SCHEMBL6506633 0.87 RAB9A (0.74) NPC1RAB9ATP53SMN1; SMN2PKM
SCHEMBL5592854 0.85 TP53 (0.69) NPC1RAB9ATP53SMN1; SMN2PKM
SCHEMBL353911 0.84 NPC1 (0.66) NPC1RAB9ATP53SMN1; SMN2PKM
SCHEMBL1177100 0.84 NPC1 (0.66) NPC1RAB9ATP53SMN1; SMN2PKM
SCHEMBL8627930 0.81 NPC1 (0.62) NPC1RAB9ATP53SMN1; SMN2PKM
SCHEMBL5866982 0.81 NPC1 (1.00) NPC1RAB9ATP53SMN1; SMN2PKM
SCHEMBL244107 0.80 FLT3 (1.00) NPC1RAB9ATP53SMN1; SMN2PKM
SCHEMBL31061078 0.80 FLT3 (1.00) NPC1RAB9ATP53SMN1; SMN2PKM
SCHEMBL23800377 0.80 NPC1 (0.60) NPC1RAB9ATP53SMN1; SMN2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115228617-B 3-Allyl salicylhydroxamic acid compound, preparation thereof and application thereof in metal ore flotation 中南大学 2025-03-14 CN disclosed
CN-111841896-B Benzo-heterocycle hydroximic acid collecting agent and preparation method and application thereof 武汉工程大学 2022-10-18 CN disclosed
CN-111848591-B HDAC inhibitors and methods of making and using the same 成都先导药物开发股份有限公司 2022-03-18 CN disclosed