Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30407915 | 1.00 | NR1H2 (0.45) | NR1H2JAK2JAK1NR1D1PIK3CD | |
| SCHEMBL28891309 | 1.00 | NR1H2 (0.45) | NR1H2JAK2JAK1NR1D1PIK3CD | |
| SCHEMBL20521721 | 0.87 | PIK3CD (0.43) | NR1H2JAK2JAK1NR1D1PIK3CD | |
| SCHEMBL3564630 | 0.86 | NR1H2 (0.48) | NR1H2JAK2JAK1NR1D1KDM4E | |
| SCHEMBL1996182 | 0.86 | NR1H2 (0.48) | NR1H2JAK2JAK1NR1D1KDM4E | |
| SCHEMBL3568388 | 0.86 | NR1H2 (0.48) | NR1H2JAK2JAK1NR1D1KDM4E | |
| SCHEMBL31567025 | 0.85 | NR1H2 (0.43) | NR1H2JAK2JAK1NR1D1KDM4E | |
| SCHEMBL23910185 | 0.83 | JAK2 (0.41) | NR1H2JAK2JAK1NR1D1KDM4E | |
| SCHEMBL22125032 | 0.83 | JAK2 (0.41) | NR1H2JAK2JAK1NR1D1KDM4E | |
| SCHEMBL5570674 | 0.82 | HPGD (0.51) | NR1H2KDM4EPKMGPR119HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230121952-A1 | COMPOUNDS | INFLAZOME LIMITED (IE) | 2023-04-20 | — | — | US | disclosed |
| CN-115362152-A | Compound (I) | 英夫拉索姆有限公司 | 2022-11-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230121952-A1 | COMPOUNDS | NLRP3, NOD1, PYCARD | NR1H2 702/4885JAK2 764/4885JAK1 1940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.