Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | CTSD | P07339 | 2/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2878332 | 0.83 | TAAR1 (0.46) | ABCC9TAAR1 | |
| SCHEMBL2875832 | 0.77 | ABCC9 (0.37) | ABCC9KDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL2875833 | 0.77 | ABCC9 (0.37) | ABCC9KDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL2875733 | 0.75 | TAAR1 (0.36) | ABCC9KDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL2878735 | 0.74 | ABCB1 (0.53) | ABCB1ABCC9KDM4ECYP3A4CYP2C19 | |
| SCHEMBL2009405 | 0.74 | ABCB1 (0.53) | ABCB1ABCC9KDM4ECYP3A4CYP2C19 | |
| SCHEMBL2889144 | 0.73 | ABCB1 (0.43) | ABCB1KDM4ECYP3A4CYP2C19HIF1A | |
| SCHEMBL2881077 | 0.73 | ABCB1 (0.43) | ABCB1ABCC9KDM4ECYP3A4CYP2C19 | |
| SCHEMBL3596079 | 0.73 | ABCB1 (0.43) | ABCB1ABCC9KDM4ECYP3A4CYP2C19 | |
| SCHEMBL2008331 | 0.73 | ABCB1 (0.43) | ABCB1ABCC9KDM4ECYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7652008-B2 | 2,2,7,9-tetramethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-3-ol; 3-hydroxy-2,2,9-trimethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-7-carbonitrile; have the prolongation effect on refractory period | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-01-26 | — | — | US | disclosed |