Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.47 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CCND3 | P30281 | 1/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | EML4 | Q9HC35 | 4/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.43 |
| ▸ | FLT3 | P36888 | 4/20 | 0.43 |
| ▸ | RET | P07949 | 3/20 | 0.43 |
| ▸ | ROS1 | P08922 | 3/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28891739 | 0.87 | SLC2A1 (0.39) | SLC2A1AURKACDK2CCNA2ADRA2A | |
| SCHEMBL28891651 | 0.81 | SLC2A1 (0.54) | SLC2A1TNIKAURKACDK2CDK4 | |
| SCHEMBL11029146 | 0.79 | SLC2A1 (0.49) | SLC2A1TNIKAURKACDK2CDK4 | |
| Trifluoroacetic Acid SCHEMBL29876164 | 0.79 | ADRA2A (0.55) | SLC2A1TNIKAURKACDK2CDK4 | |
| Trifluoroacetic Acid SCHEMBL28891676 | 0.79 | ADRA2A (0.55) | SLC2A1TNIKAURKACDK2CDK4 | |
| SCHEMBL30007675 | 0.74 | CHEK1 (0.57) | SLC2A1AURKACDK2CDK4CCNA2 | |
| SCHEMBL28862907 | 0.74 | CHEK1 (0.57) | SLC2A1AURKACDK2CDK4CCNA2 | |
| SCHEMBL11033969 | 0.74 | SLC2A1 (0.56) | SLC2A1TNIKAURKACDK2CDK4 | |
| SCHEMBL11027974 | 0.73 | SLC2A1 (0.54) | SLC2A1AURKACDK2CDK4CCNA2 | |
| SCHEMBL29875994 | 0.73 | KDM4E (0.41) | SLC2A1TNIKEML4ALKFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197154-A | HPK1 inhibitor and application thereof in medicine | 贝达药业股份有限公司 | 2022-10-18 | — | — | CN | disclosed |