SCHEMBL28891958

SCHEMBL28891958

CC(C)(C)c1cccc(Oc2ccc(C(=O)O)c(C(=O)O)c2)c1C(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.48
KDM4E B2RXH2 1/20 0.48
PYGM P11217 12/20 0.47
HPSE Q9Y251 1/20 0.46
TDP1 Q9NUW8 3/20 0.46
DUSP3 P51452 1/20 0.46
PTPN5 P54829 1/20 0.46
PTPN11 Q06124 1/20 0.46
PYGL P06737 11/20 0.45
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.43
GALK1 P51570 1/20 0.42
CASP6 P55212 1/20 0.42
MCL1 Q07820 1/20 0.42
PLEC Q15149 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847757 0.83 ALDH1A1 (0.51) POLBKDM4EPYGMHPSETDP1
SCHEMBL29441966 0.82 POLB (0.52) POLBKDM4EPYGMHPSETDP1
SCHEMBL310396 0.82 POLB (0.52) POLBKDM4EPYGMHPSETDP1
SCHEMBL31625580 0.81 POLB (0.51) POLBKDM4EPYGMHPSETDP1
SCHEMBL7965762 0.80 POLB (0.50) POLBKDM4EPYGMHPSETDP1
SCHEMBL26361730 0.78 ESRRA (0.35) TDP1ALDH1A1
SCHEMBL31152670 0.78 POLB (0.56) POLBKDM4EPYGMHPSETDP1
SCHEMBL9847753 0.78 RARB (0.51) POLBKDM4EPYGMTDP1DUSP3
SCHEMBL7969637 0.77 POLB (0.65) POLBKDM4EPYGMHPSETDP1
SCHEMBL29664286 0.77 POLB (0.65) POLBKDM4EPYGMHPSETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111234218-B Preparation method of soluble polyimide containing amino phenylsulfonyl hexafluoropropane structure 桂林理工大学 2022-12-27 CN claimed
CN-111234218-A Preparation method of soluble polyimide containing amino phenylsulfonyl hexafluoropropane structure 桂林理工大学 2020-06-05 CN claimed
CN-111234218-B Preparation method of soluble polyimide containing amino phenylsulfonyl hexafluoropropane structure 桂林理工大学 2022-12-27 CN disclosed
CN-111234218-A Preparation method of soluble polyimide containing amino phenylsulfonyl hexafluoropropane structure 桂林理工大学 2020-06-05 CN disclosed