SCHEMBL2889225

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2880797	0.91	PDE5A (0.52)	CYP2D6CYP1A2CYP3A4ALDH1A1LMNA
	SCHEMBL2889690	0.85	NPSR1 (0.55)	CYP2D6CYP1A2CYP3A4ALDH1A1LMNA
	SCHEMBL2889462	0.83	CYP1A2 (0.43)	CYP2D6CYP1A2CYP3A4ALDH1A1LMNA
	SCHEMBL4483522	0.73	CYP1A2 (0.56)	CYP2D6CYP1A2CYP3A4ALDH1A1LMNA
	SCHEMBL29696619	0.71	ESR1 (0.48)	CYP2D6CYP3A4ALDH1A1LMNACYP2C19
	SCHEMBL28458542	0.71	ESR1 (0.48)	CYP2D6CYP3A4ALDH1A1LMNACYP2C19
	SCHEMBL17039004	0.71	TDP1 (0.50)	CYP2D6CYP1A2CYP3A4ALDH1A1LMNA
	SCHEMBL29459606	0.71	TDP1 (0.50)	CYP2D6CYP1A2CYP3A4ALDH1A1LMNA
	SCHEMBL5110734	0.71	PDE5A (0.84)	CYP2D6CYP1A2CYP3A4ALDH1A1LMNA
	SCHEMBL928140	0.69	PTGER4 (0.50)	CYP2D6CYP1A2CYP3A4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.