Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | BUB1 | O43683 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889462 | 0.89 | CYP1A2 (0.43) | NPSR1TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2889225 | 0.85 | CYP2D6 (0.44) | NPSR1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2880797 | 0.81 | PDE5A (0.52) | CYP1A2CYP3A4CYP2D6CYP2C9PMP22 | |
| SCHEMBL19128354 | 0.74 | CYP1A2 (0.65) | NPSR1TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14584085 | 0.74 | CYP1A2 (0.65) | NPSR1TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5320369 | 0.74 | NR1H2 (0.43) | — | |
| SCHEMBL5321077 | 0.74 | NR1H2 (0.42) | LMNAKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL5318243 | 0.74 | CCR2 (0.36) | BUB1HTTPOLB | |
| SCHEMBL928760 | 0.72 | CYP1A2 (0.66) | NPSR1TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16366286 | 0.72 | CYP1A2 (0.62) | NPSR1TSHRCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113507-A1 | 3-Tetrazolyl Indazoles, 3-Tetrazolyl Pyrazolopyridines, and use Thereof | BAYER HEALTHCARE AG (DE) | 2010-05-06 | — | — | US | claimed |
| US-20100113507-A1 | 3-Tetrazolyl Indazoles, 3-Tetrazolyl Pyrazolopyridines, and use Thereof | BAYER HEALTHCARE AG (DE) | 2010-05-06 | — | — | US | disclosed |
| EP-2024361-A1 | 3-TETRAZOLYL INDAZOLES, 3-TETRAZOLYL PYRAZOLOPYRIDINES, AND USE THEREOF | Bayer HealthCare AG (DE) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007128454-A1 | 3-TETRAZOLYL INDAZOLES, 3-TETRAZOLYL PYRAZOLOPYRIDINES, AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113507-A1 | 3-Tetrazolyl Indazoles, 3-Tetrazolyl Pyrazolopyridines, and use Thereof | TNNI3, FABP3, PPIP5K2 | NPSR1 2634/4885TSHR 1683/4885CYP1A2 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.